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With regard to nicotine use disorder, a randomized trial evaluating dulaglutide for smoking cessation found that abstinence rates at 12 weeks did not differ significantly between the dulaglutide and placebo groups (Lengsfeld et al., 2023)
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The hepatoprotective effect seen with NAC may be due to its ability to effectively detoxify arsenics electrophiles and cause its rapid elimination/excretion from the body
The trial was in a general overweight/obese adult population, not in GLP-1 users
Elevated GH can affect insulin sensitivity, so this is worth tracking for patients with any metabolic history
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