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The medication is not suitable for patients with a personal or family history of medullary thyroid carcinoma (MTC), MEN 2 syndrome (multiple endocrine neoplasia type 2 syndrome), or pancreatitis

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"This is the first clinical trial to demonstrate that semaglutide may improve liver fibrosis in patients with advanced MASH, including those with compensated cirrhosis," said Rohit Loomba, MD, senior author of the study, gastroenterologist and hepatologist at UC San Diego Health and chief of the Division of Gastroenterology and Hepatology at UC San Diego School of Medicine

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The 2026 Regulatory Landscape The legal foundation for compounded GLP-1 medications shifted in early 2026

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Recent safety reviews have examined whether semaglutide medicines, including Wegovy, may be associated with non-arteritic anterior ischemic optic neuropathy, or NAION

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Nutrients, 17 (8), 1303

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