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(Comprehensive review detailing the inter-related roles of B-complex vitamins in cellular metabolism, energy production, and neurological function)

by increasing stomach acidity or liver enzyme elevations)

Patients on those medications should only receive B-Complex injections with close monitoring (and dosage adjustments of the anticonvulsant if needed)

On the other hand, several drugs can deplete pyridoxine or heighten its requirement

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[8] Although not an absolute contraindication, patients with coronary artery disease or unstable angina should only use B-Complex injections containing niacinamide under physician supervision, since high-dose niacin supplements have been linked to arrhythmias in such patients