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Severe adverse cutaneous reactions to drugs
This discrepancy between formal trial data and patient-reported experiences may reflect several factors: cold sensitivity might not have been specifically monitored in trials, it may be attributed to weight loss rather than the medication, or it might affect only a subset of patients
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GLP-1 (Glucagon-Like Peptide-1) medications are a class of drugs used primarily to treat type 2 diabetes
The animal study results are promising enough that it has become one of the most widely self-administered research peptides, but the absence of human trial data means all dosing is extrapolated from animal models adjusted for body weight.
FDA doesnt use DEXA for these (theyd use it for bone density tho), despite it also being the gold standard for body composition
