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Disclaimer *The mention of up to 22.5% body weight loss refers to results observed in clinical studies of Mounjaro (tirzepatide) for weight management
A genomic mutational constraint map using variation in 76,156 human genomes
The most frequently reported AEs were gastrointestinal disorders (61% of subjects), which increased in frequency with longer post-dose fasting periods and thus with higher semaglutide exposure
The brand name reflects the FDA-approved indication
Clinical encounters, prescriptions, and diagnoses were required to occur between January 1, 2021, and April 2024, a period selected to capture contemporary use of semaglutide following its U.S
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