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Sarah Whitmire was employed at Real World Analytics & Insights at the time of the study and has also received funding from Novo Nordisk Inc

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Many people achieve excellent, lasting weight loss and blood sugar control on semaglutide, and its long-term safety and cardiovascular benefit profile is well established

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These shiftsoften related to fat loss and skin changesare most seen when someone quickly loses weight, explains Natasha Bhuyan, MD, a board-certified family physician at Amazon One Medical in Phoenix

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While initial clinical observations indicate promising effects in specific conditions such as diabetic peripheral neuropathy, irritable bowel syndrome, and idiopathic intracranial hypertension, rigorous clinical trials are needed to confirm their efficacy, elucidate weight-loss-independent mechanisms, and establish comprehensive safety profiles across various pain conditions

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Cardiovasc Diabetol 20:36 Perkovic V, Tuttle KR, Rossing P, FLOW Trial Committees and Investigators et al (2024) Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes

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