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Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease

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Scherer, P., Hill, J

3.3 mPTP identification and sensitivity of mPTP to calcium in the heart of glutathione-treated old rats Figure 2 shows typical kinetic curves of spontaneous mitochondrial swelling in Ca 2+ free medium and under conditions of calcium loading as well as changes in sensitivity of mitochondria to a wide range of Ca 2+ concentration under our study conditions

Related peptides used to investigate these signaling pathways may also be available within the NewBioRx catalog to support laboratory research in cellular signaling and structural biology