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& Minna, J
CLINICAL TRIAL EVIDENCE FOR DUAL GLP-1/GLUCAGON RAs AND TRIPLE AGONISTS IN MASH Survodutide Survodutide, a weekly dual GLP-1/GCG agonist, was assessed in a phase 2 dose-finding trial (NCT04771273) including 293 individuals with histologically confirmed MASH and fibrosis stages F1-F3 [46]
Interestingly, a recent study has demonstrated a dose-dependent requirement of cultured myoblasts for TGF-
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For confirmed significant deficiency, a loading protocol with more frequent injections may be recommended initially
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