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Your provider may adjust your dose during the first month to optimize your response speed

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When to seek medical advice: Severe or persistent abdominal pain (especially if radiating to back or shoulder) Persistent vomiting or inability to keep fluids down Yellowing of the skin or eyes (jaundice) Chest pain or persistent palpitations Unexplained changes in blood glucose levels Difficulty adhering to medication or diabetes management plans Concerns about substance use or mental health For urgent concerns, contact NHS 111 for advice

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doi: 10.1056/NEJMoa1509225 5 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

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