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The patients most likely to show a divergent psychiatric response to GLP-1 therapy those with comorbid SUD, prior mood episode history, or active anhedonia at baseline are exactly the patients who get excluded for psychiatric instability. The result is a Phase 3 dataset that proves efficacy in a population cleaner than anyone sitting in an actual psychiatric clinic
10.1038/sj.jhh.1001979 226 OkamotoT.MasuharaM.IkutaK
Hepatic NAD + deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing
Also, it made me very sleepy
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