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In studies involving nonhuman primates, GSBR-1290 showed a dose-dependent increase in insulin secretion, improved glucose control, and a decrease in both food intake and body weight

Kim et al., 2010

Never aim the stream directly at the lyophilized cake

The paraventricular nucleus integrates these signals and coordinates downstream responses including reduced food intake

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GLP-1 Medications and Gallbladder Risk in Patients Who Still Have One For patients with an intact gallbladder, some observational data suggests that rapid weight loss from GLP-1 therapy may increase the risk of gallstone formation, particularly during the initial weeks of treatment